Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 7/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7283249 | 0.91 | ITGB3 (0.39) | ITGB3ITGA2BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7276387 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL7273468 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL7276103 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7272723 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7273383 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7281006 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7283412 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7275736 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1LMNAMAPT | |
| SCHEMBL7275190 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BMAPTF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |