Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499515 | 0.80 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DCHEK2 | |
| SCHEMBL7439701 | 0.78 | ALDH1A1 (0.60) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7281201 | 0.78 | PDE4A (0.58) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4599581 | 0.76 | ERN1 (0.72) | PDE4APDE4BPDE4CPDE4DCHEK2 | |
| SCHEMBL7077723 | 0.76 | MAPK1 (0.57) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10804813 | 0.76 | ALDH1A1 (0.51) | ARMAPK1CA1CA2 | |
| SCHEMBL4455295 | 0.76 | CA1 (0.65) | MAPK1CA1CA2 | |
| SCHEMBL8729926 | 0.74 | MAPT (0.58) | CA1CA2 | |
| SCHEMBL28259429 | 0.74 | FYN (0.67) | PDE4APDE4BPDE4CPDE4DCHEK2 | |
| SCHEMBL26628336 | 0.74 | PARP10 (0.61) | PDE4APDE4BPDE4CPDE4DCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |