SCHEMBL7274048

SCHEMBL7274048

Nc1cc(OCC2CC2)c(C(=O)NC2CC3CCC(C2)N3)cc1Cl

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 7/20 0.73
DRD2 P14416 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9021893 0.84 HTR4 (0.98) HTR4DRD2
SCHEMBL10523919 0.83 HTR4 (0.76) HTR4DRD2
SCHEMBL10412169 0.83 HTR4 (0.76) HTR4DRD2
Hydrochloric Acid SCHEMBL9022289 0.80 HTR4 (0.89) HTR4DRD2
SCHEMBL4895970 0.77 HTR4 (0.70) HTR4DRD2
SCHEMBL7266033 0.76 HTR4 (0.44) HTR4DRD2
SCHEMBL8364917 0.76 GAA (0.63) HTR4
Pancopride SCHEMBL120427 0.75 HTR3A (0.74)
SCHEMBL8052736 0.75 HTR4 (0.52) HTR4
SCHEMBL23999723 0.74 HTR3A (0.67) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4937236-A Anxiolytic N-substituted benzamides FORDONAL, S.A. (ES) 1990-06-26 US disclosed
US-4877780-A ANTIEMETIC AGENTS FORDONAL, S.A. (ES) 1989-10-31 US disclosed
EP-0302699-A2 Improvements relating to n-substituted benzamides WALTON S.A. (ES) 1989-02-08 EP disclosed