SCHEMBL727427

SCHEMBL727427

NC(=O)C1CC(=O)[N]C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5393475 0.81 ALDH1A1 (0.36)
SCHEMBL28645452 0.69
SCHEMBL6406314 0.68
SCHEMBL6401076 0.66
SCHEMBL4470135 0.64
SCHEMBL23009324 0.62
SCHEMBL4078350 0.62 EPHX1 (0.32)
SCHEMBL4789428 0.61 SIRT1 (0.31)
SCHEMBL4580944 0.60
SCHEMBL4580166 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200178-B1 COMPOSITE MEMBRANE WITH POLYALKYLENE OXIDE MODIFIED POLYAMIDE SURFACE DOW GLOBAL TECHNOLOGIES INC (US) 2008-11-12 EP claimed
EP-1200178-A1 COMPOSITE MEMBRANE WITH POLYALKYLENE OXIDE MODIFIED POLYAMIDE SURFACE THE DOW CHEMICAL COMPANY (US) 2002-05-02 EP claimed
US-6280853-B1 CROSSLINKED POLYAMIDES ON SUPPORTS WITH GRAFTING POLYOXYALKYLENE OXIDE GROUPS THE DOW CHEMICAL COMPANY 2001-08-28 US claimed
WO-2000076641-A1 COMPOSITE MEMBRANE WITH POLYALKYLENE OXIDE MODIFIED POLYAMIDE SURFACE THE DOW CHEMICAL COMPANY (US) 2000-12-21 WO claimed
US-8757396-B2 Composite membrane with coating comprising polyalkylene oxide and oxy-substituted phenyl compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-24 US disclosed
US-8733558-B2 Composite membrane with coating comprising polyalkylene oxide and biguanide-type compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-27 US disclosed
US-8721942-B2 Composite membrane including coating of polyalkylene oxide and acetophenone compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-13 US disclosed
US-8646616-B2 Composite membrane with coating comprising polyalkylene oxide and imidazol compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-11 US disclosed
US-8640886-B2 Composite membrane including coating of polyalkylene oxide and triazine compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-04 US disclosed
WO-2011149573-A1 POLYAMIDE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND OXY- SUBSTITUTED PHENYL COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-01 WO disclosed
WO-2011149571-A1 POLYAMIDE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND BIGUANIDE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-01 WO disclosed
WO-2011149572-A1 POLYAMIDE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-01 WO disclosed
WO-2010065276-A1 POLYAMIDE MEMBRANE WITH COATING OF POLYALKYLENE OXIDE AND POLYACRYLAMIDE DOW GLOBAL TECHNOLOGIES INC. (US) 2010-06-10 WO disclosed
US-20100143733-A1 POLYAMIDE MEMBRANE WITH COATING OF POLYALKYLENE OXIDE AND POLYACRYLAMIDE COMPOUNDS DOW GLOBAL TECHNOLOGIES INC. 2010-06-10 US disclosed
EP-2117688-A2 MODIFIED POLYAMIDE MEMBRANE Dow Global Technologies Inc. (US) 2009-11-18 EP disclosed
US-20090194479-A1 MODIFIED POLYAMINE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC 2009-08-06 US disclosed
EP-1200178-B1 COMPOSITE MEMBRANE WITH POLYALKYLENE OXIDE MODIFIED POLYAMIDE SURFACE DOW GLOBAL TECHNOLOGIES INC (US) 2008-11-12 EP disclosed
WO-2008097786-A2 MODIFIED POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-08-14 WO disclosed
US-20080185332-A1 MODIFIED POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-08-07 US disclosed
US-6280853-B1 CROSSLINKED POLYAMIDES ON SUPPORTS WITH GRAFTING POLYOXYALKYLENE OXIDE GROUPS THE DOW CHEMICAL COMPANY 2001-08-28 US disclosed