Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 17/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287334 | 0.93 | KLK7 (0.41) | KLK7REN | |
| SCHEMBL7272612 | 0.90 | REN (0.45) | REN | |
| SCHEMBL7280285 | 0.89 | PSEN1 (0.46) | KLK7REN | |
| SCHEMBL7285856 | 0.89 | KLK7 (0.39) | KLK7REN | |
| SCHEMBL7279531 | 0.89 | REN (0.41) | KLK7REN | |
| SCHEMBL7271684 | 0.88 | REN (0.44) | KLK7REN | |
| SCHEMBL7282895 | 0.85 | KLK7 (0.42) | KLK7RENTLR2TLR1GCK | |
| SCHEMBL7287986 | 0.79 | KLK7 (0.43) | KLK7RENTLR2TLR1 | |
| SCHEMBL9011568 | 0.79 | REN (0.37) | KLK7RENGCK | |
| SCHEMBL7273810 | 0.78 | KLK7 (0.42) | KLK7REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476515-A1 | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |