Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 14/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274318 | 1.00 | GHSR (0.52) | GHSRPYGLCXCR5SMN1; SMN2GAA | |
| SCHEMBL7274311 | 1.00 | GHSR (0.52) | GHSRPYGLCXCR5SMN1; SMN2GAA | |
| SCHEMBL10720970 | 0.90 | CXCR5 (0.53) | CXCR5GAA | |
| SCHEMBL5835274 | 0.86 | GHSR (0.65) | GHSRPYGLCXCR5 | |
| SCHEMBL18614234 | 0.83 | GHSR (0.63) | GHSRPYGLCXCR5 | |
| SCHEMBL29715495 | 0.83 | GHSR (0.63) | GHSRPYGLCXCR5 | |
| SCHEMBL2813574 | 0.83 | GHSR (0.63) | GHSRPYGLCXCR5 | |
| SCHEMBL5835511 | 0.81 | GHSR (0.45) | GHSRPYGLCXCR5 | |
| SCHEMBL7268200 | 0.80 | PYGL (0.48) | GHSRPYGLCXCR5 | |
| SCHEMBL1157171 | 0.80 | EPHX2 (0.46) | GHSRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680284-A | RENNIN INHIBITORS, HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0189203-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1986-07-30 | — | — | EP | disclosed |