Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276761 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7273458 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| Hydrochloric Acid SCHEMBL7281884 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| Hydrochloric Acid SCHEMBL8573867 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7274893 | 0.85 | PPARD (0.45) | ITGB3ITGA2BPPARDPPARA | |
| SCHEMBL7280894 | 0.84 | F2 (0.43) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7276107 | 0.83 | ITGB3 (0.67) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7276120 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7274111 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL7118598 | 0.78 | ITGB3 (0.74) | ITGB3ITGA2BPRSS1TMPRSS15F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | claimed |
| EP-0567967-B1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | THOMAE GMBH DR K (DE) | 1996-07-10 | — | — | EP | claimed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | claimed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |