Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8573867 | 0.99 | ITGB3 (0.43) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7281884 | 0.99 | ITGB3 (0.43) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7280894 | 0.89 | F2 (0.43) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7280890 | 0.88 | RPS6KA3 (0.36) | RPS6KA3 | |
| SCHEMBL7281314 | 0.87 | RPS6KA3 (0.39) | RPS6KA3 | |
| SCHEMBL7276761 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7274348 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7280893 | 0.84 | F2 (0.37) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7275608 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7274822 | 0.83 | TSHR (0.37) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | claimed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | claimed |