Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275654 | 0.85 | CYP4F2 (0.43) | ALOX5OR51E2MAPTGAA | |
| SCHEMBL7273477 | 0.84 | PTPN1 (0.41) | MEN1KMT2ACA12CA2CA9 | |
| SCHEMBL7273648 | 0.84 | PTPN1 (0.41) | MEN1KMT2AMAPTGAA | |
| SCHEMBL7275304 | 0.82 | PTPN1 (0.40) | ALOX5OR51E2KMT2AMAPTGAA | |
| SCHEMBL3940302 | 0.79 | KMT2A (0.59) | ALOX5OR51E2MEN1KMT2AMAPT | |
| SCHEMBL18744079 | 0.77 | ALOX5 (0.55) | ALOX5OR51E2MEN1KMT2AMAPT | |
| Dihydroferulic Acid Methyl Ester SCHEMBL490876 | 0.77 | ALOX5 (0.77) | ALOX5OR51E2GAA | |
| SCHEMBL7272597 | 0.77 | CYP4A11 (0.51) | KMT2AMAPTCA12CA9 | |
| SCHEMBL8910707 | 0.76 | KDM4E (0.39) | MAPTGAA | |
| SCHEMBL16294204 | 0.76 | ALOX5 (0.54) | ALOX5OR51E2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |