Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.77 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrocurcumin SCHEMBL284877 | 0.87 | ALOX5 (1.00) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Tetrahydrocurcumin SCHEMBL29370299 | 0.87 | ALOX5 (1.00) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL28287006 | 0.87 | CYP19A1 (0.65) | ALOX5OR51E2TSHRCYP1A2CYP3A4 | |
| Tetrahydrocurcumin SCHEMBL29372158 | 0.87 | ALOX5 (1.00) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL28355932 | 0.87 | ALOX5 (0.88) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL3940302 | 0.87 | KMT2A (0.59) | ALOX5OR51E2ALDH1A1 | |
| Dihydroferulic Acid Ethyl Ester SCHEMBL356300 | 0.86 | ALOX5 (0.67) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL119051 | 0.85 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Dihydroferulic Acid SCHEMBL30210940 | 0.85 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL14763994 | 0.85 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114392260-A | Medicine for relieving anxiety and depression | 重庆市九龙坡区精神卫生中心(重庆市九龙坡区石坪桥医院) | 2022-04-26 | — | — | CN | claimed |
| WO-2002015691-A1 | USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK | ROBIGUS AB (SE) | 2002-02-28 | — | — | WO | claimed |
| US-20260125731-A1 | MICROORGANISMS AND METHODS FOR PRODUCING CAROTENOIDS AND OTHER COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2026-05-07 | — | — | US | disclosed |
| US-12325688-B2 | Gingerenone A prodrugs as sensotherapeutics and methods of use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250115543-A1 | GINGERENONE A PRODRUGS AS SENSOTHERAPEUTICS AND METHODS OF USE | THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-04-10 | — | — | US | disclosed |
| US-20250101441-A1 | MICROORGANISMS AND METHODS FOR PRODUCING CIS,CIS-MUCONIC ACID | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-03-27 | — | — | US | disclosed |
| CN-118206452-A | Gingerol A prodrug compound and application thereof | 陈玉松 | 2024-06-18 | — | — | CN | disclosed |
| US-11981946-B2 | Microorganisms and methods for producing 2-pyrone-4,6-dicarboxylic acid and other compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2024-05-14 | — | — | US | disclosed |
| WO-2023146771-A1 | GINGERENONE A PRODRUGS AS SENOTHERAPEUTICS AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-114392260-A | Medicine for relieving anxiety and depression | 重庆市九龙坡区精神卫生中心(重庆市九龙坡区石坪桥医院) | 2022-04-26 | — | — | CN | disclosed |
| US-11028418-B2 | Microorganisms and methods for producing 2-pyrone-4,6-dicarboxylic acid and other compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-6723740-B2 | ADMINISTERING THERAPEUTIC AMOUNT OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST TO LOWER TRIGLYCERIDES | SMITHKLINE BEECHAM CORPORATION | 2004-04-20 | — | — | US | disclosed |
| US-6710063-B1 | Activators of PPAR delta | SMITHKLINE BEECHAM CORPORATION | 2004-03-23 | — | — | US | disclosed |
| US-20030203947-A1 | Administration of a therapeutic amount of a 1,3-thiazole-5-yl methylsulfanyl or 1,3-oxazole-5-yl methylsulfanyl derivative to a patient for lowering triglycerides | CHAO ESTHER YU-HSUAN (US) | 2003-10-30 | — | — | US | disclosed |
| EP-1189895-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GLAXO GROUP LIMITED (GB) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000603-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GLAXO GROUP LIMITED (GB) | 2001-01-04 | — | — | WO | disclosed |
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |
| US-4188338-A | ANTICOAGULANTS | AKZONA INCORPORATED (US) | 1980-02-12 | — | — | US | disclosed |
| US-4173652-A | ANTICOAGULANTS | AKZONA INCORPORATED (US) | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12325688-B2 | Gingerenone A prodrugs as sensotherapeutics and methods of use | AGER, RGS16, GRIA2 | ALOX5 529/4885OR51E2 840/4885TAAR1 1403/4885 |
| US-20030203947-A1 | Administration of a therapeutic amount of a 1,3-thiazole-5-yl methylsulfanyl or 1,3-oxazole-5-yl methylsulfanyl derivative to a patient for lowering triglycerides | PPARA, PPARD, PPARG | ALOX5 548/4885OR51E2 3082/4885TAAR1 1360/4885 |
| US-20250115543-A1 | GINGERENONE A PRODRUGS AS SENSOTHERAPEUTICS AND METHODS OF USE | AGER, RGS16, GRIA2 | ALOX5 529/4885OR51E2 840/4885TAAR1 1403/4885 |
| US-20260125731-A1 | MICROORGANISMS AND METHODS FOR PRODUCING CAROTENOIDS AND OTHER COMPOUNDS | DHPS, DCXR, BLVRB | ALOX5 266/4885OR51E2 1192/4885TAAR1 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.