Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272971 | 0.99 | NAMPT (0.41) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7272690 | 0.99 | NAMPT (0.41) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7284310 | 0.99 | NAMPT (0.41) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7274533 | 0.97 | TSHR (0.40) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7274864 | 0.95 | NAMPT (0.40) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| Hydrochloric Acid SCHEMBL7283118 | 0.93 | NAMPT (0.41) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7280925 | 0.92 | LMNA (0.43) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| Hydrochloric Acid SCHEMBL7281517 | 0.91 | L3MBTL1 (0.38) | LMNATSHRNAMPTL3MBTL1ALDH1A1 | |
| Water SCHEMBL7275711 | 0.91 | LMNA (0.42) | LMNATSHRNAMPTL3MBTL1ITGB3 | |
| SCHEMBL7276721 | 0.90 | TRPV1 (0.43) | LMNAALDH1A1F2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |