Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284791 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7272581 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7281007 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7275280 | 0.86 | ITGB3 (0.42) | ITGB3ITGA2BCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7274067 | 0.86 | ITGB3 (0.42) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL7281934 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL7276107 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9254812 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL9254628 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BNQO2F2F10 | |
| Hydrochloric Acid SCHEMBL7274050 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BNQO2F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |