Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254812 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL9251193 | 0.87 | MAPT (0.47) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL9568473 | 0.87 | MAPT (0.47) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL9253224 | 0.85 | MAPT (0.47) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL9254967 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL9258402 | 0.79 | MAPT (0.48) | ITGB3ITGA2BMAPTKMT2AMEN1 | |
| SCHEMBL7274553 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7284791 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7118598 | 0.76 | ITGB3 (0.74) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9253873 | 0.75 | ITGB3 (0.56) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |