Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281590 | 0.98 | SIGMAR1 (0.44) | SIGMAR1ACACBCACNA1G | |
| SCHEMBL7283982 | 0.97 | SIGMAR1 (0.43) | SIGMAR1ACACBCHRNB4CHRNA3 | |
| SCHEMBL7284474 | 0.94 | SIGMAR1 (0.41) | SIGMAR1CHRNB4CHRNA3CACNA1G | |
| SCHEMBL7283476 | 0.90 | SIGMAR1 (0.45) | SIGMAR1CACNA1G | |
| SCHEMBL7280624 | 0.90 | SIGMAR1 (0.45) | SIGMAR1CHRNB4CHRNA3MAPT | |
| SCHEMBL7274358 | 0.89 | SIGMAR1 (0.44) | SIGMAR1CACNA1G | |
| SCHEMBL7282506 | 0.89 | SIGMAR1 (0.45) | SIGMAR1CACNA1G | |
| SCHEMBL7275517 | 0.88 | SIGMAR1 (0.43) | SIGMAR1ACACB | |
| SCHEMBL7282368 | 0.88 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL7283872 | 0.88 | SIGMAR1 (0.44) | SIGMAR1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |