Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274065 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BS1PR1F10F2 | |
| Hydrochloric Acid SCHEMBL7272076 | 0.86 | F10 (0.38) | ITGB3ITGA2BS1PR1F10F2 | |
| SCHEMBL7274080 | 0.82 | ITGB3 (0.74) | ITGB3ITGA2BS1PR1F10F2 | |
| SCHEMBL7273999 | 0.82 | S1PR1 (0.44) | ITGB3ITGA2BS1PR1PPARDPPARA | |
| SCHEMBL7283193 | 0.80 | ITGB3 (0.57) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7275941 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BS1PR1F10F2 | |
| SCHEMBL7275097 | 0.79 | S1PR1 (0.52) | ITGB3ITGA2BS1PR1PPARDPPARA | |
| SCHEMBL7284477 | 0.78 | ITGB3 (0.70) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7283073 | 0.78 | S1PR1 (0.47) | ITGB3ITGA2BS1PR1RAB9A | |
| SCHEMBL8573861 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BS1PR1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |