Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274603 | 1.00 | CTSD (0.33) | CTSD | |
| SCHEMBL9615179 | 0.83 | CTSD (0.37) | CTSD | |
| SCHEMBL7266627 | 0.81 | CTSD (0.33) | CTSD | |
| SCHEMBL7266630 | 0.81 | CTSD (0.33) | CTSD | |
| SCHEMBL7315619 | 0.79 | — | — | |
| SCHEMBL7283590 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL7280255 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL10611170 | 0.72 | CTSD (0.31) | CTSD | |
| SCHEMBL9832650 | 0.72 | CTSD (0.31) | CTSD | |
| SCHEMBL7267634 | 0.71 | HPGD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977277-A | INTERMEDIATES FOR RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-12-11 | — | — | US | disclosed |
| US-4837204-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0230266-A2 | Functionalized peptidyl aminodiols and -triols | ABBOTT LABORATORIES (US) | 1987-07-29 | — | — | EP | disclosed |
| EP-0189203-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1986-07-30 | — | — | EP | disclosed |