Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283590 | 1.00 | CTSD (0.33) | CTSD | |
| SCHEMBL9615179 | 0.85 | CTSD (0.37) | CTSD | |
| SCHEMBL7274603 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL7266627 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL7266630 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL7274599 | 0.77 | CTSD (0.33) | CTSD | |
| SCHEMBL7315619 | 0.75 | — | — | |
| SCHEMBL7335171 | 0.72 | CTSD (0.37) | CTSD | |
| SCHEMBL8681610 | 0.71 | CTSD (0.32) | CTSD | |
| SCHEMBL8681607 | 0.71 | CTSD (0.32) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389616-A | Renin inhibitor, hypotensive agent | HOFFMAN-LAROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5256645-A | Renin inhibitors; hypotensive agents | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5134123-A | Renin enzyme inhibitors for cardiovascular disorders and high blood pressure | HOFFMAN-LA ROCHE INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0332008-A2 | Peptide-like aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |