Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.44 |
| ▸ | NQO2 | P16083 | 5/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7281919 | 0.86 | TP53 (0.39) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7275218 | 0.85 | NQO2 (0.42) | ITGB3ITGA2BNQO2WDR5ALDH1A1 | |
| SCHEMBL7282771 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7275237 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7285201 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BNQO2WDR5ALDH1A1 | |
| SCHEMBL7275069 | 0.75 | ROCK2 (0.45) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7393228 | 0.75 | NQO2 (0.39) | NQO2WDR5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7274818 | 0.74 | NQO2 (0.38) | NQO2WDR5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7283396 | 0.73 | NQO2 (0.49) | ITGB3ITGA2BNQO2WDR5 | |
| SCHEMBL7273726 | 0.72 | ITGB3 (0.46) | ITGB3ITGA2BNQO2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |