Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15237366 | 0.85 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL2633835 | 0.83 | KMT2A (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL2633836 | 0.83 | RORC (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL25188768 | 0.81 | CYP4F2 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL24036211 | 0.80 | KMT2A (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL34475417 | 0.80 | MMP1 (0.34) | CYP4F2CYP4A11 | |
| SCHEMBL6152526 | 0.80 | — | — | |
| SCHEMBL2633828 | 0.80 | CYP4F2 (0.49) | CYP4F2CYP4A11 | |
| SCHEMBL34476313 | 0.80 | CYP4F2 (0.49) | CYP4F2CYP4A11 | |
| SCHEMBL6063404 | 0.80 | CYP2C19 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512831-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5455243-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5281585-A | Secondary amide containing antagonist | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1992019595-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1992-11-12 | — | — | WO | disclosed |
| EP-0512831-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |