Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273020 | 0.98 | DRD4 (0.35) | DRD4NAMPTHTR1AHTR2AHRH1 | |
| SCHEMBL7284708 | 0.91 | OPRM1 (0.35) | DRD4HTR1AHTR2AHRH1OPRM1 | |
| SCHEMBL7274705 | 0.89 | MCHR1 (0.37) | DRD4HTR1AHTR2AHRH1OPRM1 | |
| SCHEMBL7278829 | 0.87 | KAT6A (0.35) | DRD4HTR1AHTR2AHRH1OPRM1 | |
| SCHEMBL7273363 | 0.87 | MMP12 (0.37) | HRH1 | |
| SCHEMBL7274972 | 0.83 | NAMPT (0.40) | DRD4NAMPTHTR1APIN1 | |
| SCHEMBL7281190 | 0.81 | NAMPT (0.42) | DRD4NAMPTOPRM1 | |
| SCHEMBL7273510 | 0.81 | XIAP (0.32) | — | |
| SCHEMBL7273026 | 0.80 | NAMPT (0.40) | DRD4NAMPTHTR1AOPRM1 | |
| SCHEMBL7275707 | 0.80 | OPRM1 (0.35) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |