Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739937 | 0.97 | — | — | |
| SCHEMBL7292038 | 0.88 | — | — | |
| SCHEMBL9800480 | 0.82 | P2RX1 (0.42) | P2RX1 | |
| SCHEMBL10510142 | 0.78 | — | — | |
| SCHEMBL7279661 | 0.78 | — | — | |
| SCHEMBL9800527 | 0.78 | P2RX1 (0.41) | P2RX1 | |
| SCHEMBL7290665 | 0.71 | P2RX1 (0.46) | P2RX1 | |
| SCHEMBL7433840 | 0.71 | P2RX1 (0.46) | P2RX1 | |
| SCHEMBL7277076 | 0.71 | P2RX1 (0.46) | P2RX1 | |
| SCHEMBL8910700 | 0.71 | REN (0.40) | P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |