Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 7/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577491 | 0.82 | TACR3 (0.49) | TACR3NOTUMUSP30ALPLCA9 | |
| SCHEMBL5260126 | 0.81 | GSK3B (0.45) | TACR3ALPLCA12CA9RPA1 | |
| SCHEMBL7277324 | 0.80 | CASP1 (0.46) | TACR3NOTUMUSP30ALPLCASP1 | |
| SCHEMBL15579096 | 0.79 | TACR3 (0.47) | TACR3ALPLCA9 | |
| SCHEMBL15577629 | 0.77 | NOTUM (0.45) | TACR3NOTUMUSP30ALPLCASP1 | |
| SCHEMBL16702797 | 0.75 | ALPL (0.67) | TACR3ALPLCA12CA9RPA1 | |
| SCHEMBL7275356 | 0.73 | KDM4E (0.51) | ALPL | |
| SCHEMBL29444420 | 0.71 | ALPL (0.51) | TACR3ALPLCASP1CA12CA9 | |
| SCHEMBL5230660 | 0.68 | HDAC3 (0.44) | — | |
| SCHEMBL2304283 | 0.68 | ALPL (0.51) | TACR3ALPLCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |