Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285404 | 0.92 | ITGB3 (0.52) | ITGB3ITGA2BUSP2ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL7284994 | 0.91 | USP2 (0.39) | ITGB3ITGA2BUSP2ALDH1A1NPC1 | |
| SCHEMBL7277654 | 0.91 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL7286629 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL7286641 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL7277653 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BLMNA | |
| SCHEMBL7277402 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7281127 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL7277794 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7273817 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |