Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 9/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275526 | 0.93 | PLA2G10 (0.45) | S1PR1FFAR1PLA2G10ITGB3ITGA2B | |
| SCHEMBL7275097 | 0.90 | S1PR1 (0.52) | S1PR1FFAR1ITGB3ITGA2BPPARD | |
| Hydrochloric Acid SCHEMBL8910783 | 0.85 | SIRT2 (0.40) | S1PR1ITGB3ITGA2BHDAC1 | |
| SCHEMBL7275491 | 0.85 | S1PR1 (0.52) | S1PR1FFAR1ITGB3ITGA2BPPARD | |
| SCHEMBL7273999 | 0.80 | S1PR1 (0.44) | S1PR1FFAR1ITGB3ITGA2BPPARD | |
| SCHEMBL7274314 | 0.80 | ITGB3 (0.48) | S1PR1FFAR1ITGB3ITGA2BPPARD | |
| SCHEMBL8573861 | 0.80 | ITGB3 (0.47) | S1PR1FFAR1ITGB3ITGA2BPPARD | |
| SCHEMBL7272781 | 0.79 | S1PR1 (0.46) | S1PR1ITGB3ITGA2BMEN1NPC1 | |
| SCHEMBL7275290 | 0.79 | SIRT2 (0.42) | PRMT1HDAC1 | |
| Propylamine SCHEMBL8911584 | 0.78 | S1PR1 (0.55) | S1PR1FFAR1ITGB3ITGA2BPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |