Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251785 | 1.00 | TMPRSS2 (0.41) | TMPRSS2ITGB3ITGA2BITGAVHTR1A | |
| SCHEMBL7277666 | 0.97 | TMPRSS2 (0.41) | TMPRSS2ITGB3ITGA2BITGAVHTR1A | |
| SCHEMBL7275068 | 0.92 | ITGB3 (0.40) | TMPRSS2ITGB3ITGA2BITGAV | |
| SCHEMBL7283983 | 0.91 | ITGB3 (0.43) | TMPRSS2ITGB3ITGA2BITGAV | |
| SCHEMBL7275634 | 0.89 | ITGB3 (0.42) | TMPRSS2ITGB3ITGA2BITGAV | |
| SCHEMBL7286943 | 0.89 | ITGB3 (0.42) | TMPRSS2ITGB3ITGA2BITGAV | |
| SCHEMBL7275786 | 0.88 | ITGB3 (0.42) | TMPRSS2ITGB3ITGA2BITGAV | |
| SCHEMBL7286501 | 0.87 | KDM4E (0.43) | ITGB3ITGA2BHTR1A | |
| SCHEMBL7287003 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BITGAVHTR1A | |
| SCHEMBL7277853 | 0.85 | ITGB3 (0.38) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |