Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.76 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276386 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BNAAAIRAK4 | |
| SCHEMBL7277088 | 0.89 | ITGB3 (0.78) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| SCHEMBL7284188 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| SCHEMBL7283795 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| Fradafiban SCHEMBL8863359 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Fradafiban SCHEMBL380350 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7284309 | 0.87 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL7275160 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BNAAAIRAK4 | |
| Fradafiban SCHEMBL7280818 | 0.86 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7275425 | 0.85 | ITGB3 (0.81) | ITGB3ITGA2BPPARDPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | claimed |
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |