Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275467 | 1.00 | MME (0.58) | MMEECE1CAPN1LTA4H | |
| SCHEMBL7268405 | 0.92 | MME (0.59) | MMEECE1LTA4H | |
| SCHEMBL7268401 | 0.92 | MME (0.59) | MMEECE1LTA4H | |
| SCHEMBL9555616 | 0.91 | MME (0.58) | MMECAPN1LTA4H | |
| SCHEMBL11032940 | 0.88 | MME (0.55) | MMEECE1CAPN1 | |
| SCHEMBL11031852 | 0.86 | MME (0.53) | MMEECE1CAPN1 | |
| SCHEMBL11202543 | 0.84 | MME (0.64) | MMEECE1LTA4H | |
| SCHEMBL7269082 | 0.84 | GPR132 (0.49) | MMEECE1 | |
| SCHEMBL7269089 | 0.84 | GPR132 (0.49) | MMEECE1 | |
| SCHEMBL11032335 | 0.84 | MME (0.50) | MMEECE1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |