Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269082 | 1.00 | GPR132 (0.49) | GPR132NPSR1TSHRPTPN1PPARG | |
| SCHEMBL7277521 | 0.88 | HPRT1 (0.50) | NPSR1PTPN1L3MBTL1MMEALPI | |
| SCHEMBL7277515 | 0.88 | HPRT1 (0.50) | NPSR1PTPN1L3MBTL1MMEALPI | |
| SCHEMBL9555608 | 0.84 | LTA4H (0.49) | NPSR1L3MBTL1MME | |
| SCHEMBL7275467 | 0.84 | MME (0.58) | MMEECE1 | |
| SCHEMBL7275477 | 0.84 | MME (0.58) | MMEECE1 | |
| SCHEMBL29940571 | 0.79 | FOLH1 (0.50) | L3MBTL1MMECA2CA1SLC7A5 | |
| SCHEMBL4398752 | 0.79 | MME (0.53) | NPSR1PTPN1L3MBTL1MMENAALAD2 | |
| SCHEMBL4398757 | 0.79 | MME (0.53) | NPSR1PTPN1L3MBTL1MMENAALAD2 | |
| SCHEMBL476018 | 0.76 | GPR34 (0.62) | GPR132PPARGMMEGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |