Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267085 | 1.00 | STING1 (0.42) | STING1ACHETUBB4ATUBBTUBA3C | |
| SCHEMBL7267092 | 1.00 | STING1 (0.42) | STING1ACHETUBB4ATUBBTUBA3C | |
| SCHEMBL9540978 | 0.83 | MAPK1 (0.43) | STING1HPGD | |
| SCHEMBL9540983 | 0.83 | MAPK1 (0.43) | STING1HPGD | |
| SCHEMBL9808648 | 0.78 | CA2 (0.47) | KDM4EHPGD | |
| SCHEMBL7274175 | 0.78 | BACE1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7274183 | 0.78 | BACE1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7275954 | 0.78 | BACE1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7032634 | 0.77 | CYP2A6 (0.51) | STING1ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL7267852 | 0.74 | HSD17B10 (0.39) | STING1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352832-B1 | COMPOUNDS WITH BRONCHODILATOR ACTIVITY | AKZO N.V. (NL) | 1992-05-06 | — | — | EP | disclosed |
| US-5026724-A | Benzothiophene derivatives | AKZO N.V. (NL) | 1991-06-25 | — | — | US | disclosed |
| EP-0352832-A1 | Compounds with bronchodilator activity | AKZO N.V. (NL) | 1990-01-31 | — | — | EP | disclosed |