Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282545 | 0.90 | THRB (0.56) | THRBTHRA | |
| SCHEMBL7273908 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL7273916 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL7273827 | 0.83 | THRB (0.61) | THRBTHRA | |
| SCHEMBL7284512 | 0.80 | THRB (0.58) | THRBTHRA | |
| SCHEMBL7274030 | 0.76 | THRB (0.54) | THRBTHRA | |
| SCHEMBL7276769 | 0.75 | THRB (0.53) | THRBTHRA | |
| SCHEMBL7274130 | 0.74 | THRB (0.59) | THRBTHRA | |
| SCHEMBL5858371 | 0.74 | THRB (0.78) | THRBTHRA | |
| SCHEMBL7273586 | 0.73 | THRB (0.64) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061798-A | Intermediates in the formation of synthetic hormones, mimic effects of thyroid hormones; little or no effect on the heart | SMITH KLINE & FRENCH LABORATORIES, LTD. (GB) | 1991-10-29 | — | — | US | disclosed |
| EP-0188351-B1 | CHEMICAL COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| US-4910305-A | Containing a protected 4-hydroxyphenyl | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-03-20 | — | — | US | disclosed |
| US-4826876-A | WITHOUT EFFECT ON HEART | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-05-02 | — | — | US | disclosed |
| US-4766121-A | NOT AFFECTING THE HEART | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1988-08-23 | — | — | US | disclosed |