Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284247 | 0.92 | HTR1A (0.37) | EP300HTR1ADRD4HTR2AHRH1 | |
| SCHEMBL7275885 | 0.88 | EP300 (0.40) | EP300HTR1ADRD4HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7285462 | 0.87 | F2 (0.34) | — | |
| SCHEMBL7282551 | 0.87 | ABCB1 (0.44) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7274151 | 0.87 | ABCB1 (0.44) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7281268 | 0.87 | ABCB1 (0.44) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7285879 | 0.85 | BCHE (0.33) | EP300HTR1ADRD4HTR2AHRH1 | |
| SCHEMBL7274458 | 0.85 | ABCB1 (0.43) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7274992 | 0.83 | ABCB1 (0.35) | EP300HTR1ADRD4HTR2AHRH1 | |
| SCHEMBL7273850 | 0.82 | ABCB1 (0.46) | ABCB1HPGDABCG2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |