Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL2434380 | 1.00 | — | — | |
| Thiosulfuric Acid SCHEMBL28216026 | 0.85 | BLM (0.42) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL170524 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL28148838 | 0.84 | BLM (0.59) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL1318239 | 0.84 | BLM (0.59) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL10539875 | 0.81 | KDM4E (0.50) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL4167092 | 0.80 | BLM (0.56) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL4162831 | 0.80 | BLM (0.56) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL22127325 | 0.80 | BLM (0.56) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Thiosulfuric Acid SCHEMBL21683091 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12539510-B2 | Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge | CEPHEID (US) | 2026-02-03 | — | — | US | claimed |
| US-20240141415-A1 | INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE | CEPHEID (US) | 2024-05-02 | — | — | US | claimed |
| EP-3551332-B1 | INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE | CEPHEID (US) | 2024-01-10 | — | — | EP | claimed |
| US-20220226809-A1 | INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE | CEPHEID (US) | 2022-07-21 | — | — | US | claimed |
| JP-4785315-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| EP-2049677-B1 | METHOD FOR ISOLATING CELLS | MERCK PATENT GMBH (DE) | 2011-07-20 | — | — | EP | claimed |
| EP-1254075-B1 | NONABORATE COMPOSITIONS AND THEIR PREPARATION | UNITED STATES BORAX INC (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1254075-A4 | NONABORATE COMPOSITIONS AND THEIR PREPARATION | UNITED STATES BORAX INC (US) | 2005-07-27 | — | — | EP | claimed |
| US-6919036-B2 | Reacting borate with guanidinium or imidazolidinium compound; heating; crystal structure; forming ceramic; fire retarders, microbiocide | U.S. BORAX INC. (US) | 2005-07-19 | — | — | US | claimed |
| JP-2003523964-A | — | — | 2003-08-12 | — | — | JP | claimed |
| US-20030109751-A1 | Nonaborate compositions and their preparation | U.S. BORAX INC. | 2003-06-12 | — | — | US | claimed |
| EP-1254075-A1 | NONABORATE COMPOSITIONS AND THEIR PREPARATION | U.S. BORAX INC. (US) | 2002-11-06 | — | — | EP | claimed |
| WO-2001053201-A1 | NONABORATE COMPOSITIONS AND THEIR PREPARATION | U.S. BORAX INC. (US) | 2001-07-26 | — | — | WO | claimed |
| US-12539510-B2 | Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge | CEPHEID (US) | 2026-02-03 | — | — | US | disclosed |
| US-20240141415-A1 | INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE | CEPHEID (US) | 2024-05-02 | — | — | US | disclosed |
| EP-3551332-B1 | INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA EXPRESSION LEVELS IN AN AUTOMATED REACTION CARTRIDGE | CEPHEID (US) | 2024-01-10 | — | — | EP | disclosed |
| US-6277970-B1 | NUCLEOTIDE AND AMINO ACID SEQUENCE OF GENE INVOLVED IN PRION INFECTION; SCREENING OF INDIVIDUALS; DRUG SCREENING OF MODULATORS; RECOMBINANT EXPRESSION VECTORS AND HOST CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-08-21 | — | — | US | disclosed |
| WO-2001053201-A1 | NONABORATE COMPOSITIONS AND THEIR PREPARATION | U.S. BORAX INC. (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001032922-A2 | METHODS FOR DETECTION OF A TARGET NUCLEIC ACID SEQUENCE | STRATAGENE (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2000068382-A1 | PrP-LIKE GENE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539510-B2 | Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge | DNMT3A, DNMT1, NSUN2 | KDM4E 946/4885BLM 416/4885CYP2D6 3075/4885 |
| US-20030109751-A1 | Nonaborate compositions and their preparation | NONO, BLVRB, BRI3BP | KDM4E 851/4885BLM 324/4885CYP2D6 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.