Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308857 | 0.80 | BRS3 (0.37) | DDTLDHABRS3GABRPGABRD | |
| SCHEMBL31207938 | 0.80 | BRS3 (0.37) | DDTLDHABRS3GABRPGABRD | |
| SCHEMBL22717406 | 0.79 | GPR35 (0.46) | AKR1C3AKR1C2XDH | |
| SCHEMBL30282681 | 0.79 | GPR35 (0.46) | AKR1C3AKR1C2XDH | |
| SCHEMBL29573949 | 0.79 | GPR35 (0.46) | AKR1C3AKR1C2XDH | |
| SCHEMBL21063471 | 0.78 | GABRP (0.39) | LDHAXDHGABRPGABRDGABRA1 | |
| SCHEMBL29914342 | 0.77 | DDT (0.74) | DDTLDHAPTPN1HNF4AAKR1C3 | |
| SCHEMBL686861 | 0.77 | DDT (0.74) | DDTLDHAPTPN1HNF4AAKR1C3 | |
| SCHEMBL7222569 | 0.76 | MYC (0.50) | LDHAHNF4ABRS3XDHSLC22A12 | |
| SCHEMBL9256985 | 0.76 | SLC22A12 (0.56) | PTPN1HNF4APTGDR2XDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |