⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860464 | 0.80 | — | — | |
| SCHEMBL12269119 | 0.78 | LMNA (0.40) | — | |
| SCHEMBL2145973 | 0.77 | — | — | |
| SCHEMBL8389488 | 0.75 | — | — | |
| SCHEMBL28796528 | 0.75 | TSHR (0.50) | — | |
| SCHEMBL28024343 | 0.75 | — | — | |
| SCHEMBL271356 | 0.75 | — | — | |
| SCHEMBL283526 | 0.75 | — | — | |
| SCHEMBL2625315 | 0.75 | — | — | |
| SCHEMBL801027 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372892-B2 | Attached, high reactivity rigid polyurethane foams | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-12 | — | — | US | claimed |
| EP-1725600-B2 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-10-03 | — | — | EP | claimed |
| JP-4824670-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1725600-B1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-09-03 | — | — | EP | claimed |
| US-20080038461-A1 | Attached, High Reactivity Rigid Polyurethane Foams | DOW GLOBAL TECHNOLOGIES LLC | 2008-02-14 | — | — | US | claimed |
| JP-2007528434-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1725600-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | The Dow Global Technologies Inc. (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005090431-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2005-09-29 | — | — | WO | claimed |
| US-20210040083-A1 | GCN2 INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-02-11 | — | — | US | disclosed |
| US-10793563-B2 | GCN2 inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2020-10-06 | — | — | US | disclosed |
| US-20190233411-A1 | GCN2 INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-08-01 | — | — | US | disclosed |
| EP-2736694-B1 | METHOD FOR FILLING HOLLOW CAVITIES WITH POLYMER FOAM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-07-10 | — | — | EP | disclosed |
| CN-105593264-A | Epoxy liquid curing agent compositions | AIR PROD & CHEM | 2016-05-18 | — | — | CN | disclosed |
| US-9238039-B2 | Pyrazolo[1,5-A]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-20080015177-A1 | S1P receptor modulating compounds and use thereof | AMGEN INC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007040617-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS CONTAINING OXAZOLIDONE GROUPS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070059512-A1 | Attached, high reactivity rigid polyurethane foams containing oxazolidone groups | DOW GLOBAL TECHNOLOGIES INC. | 2007-03-15 | — | — | US | disclosed |
| EP-1725600-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | The Dow Global Technologies Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005090431-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| US-4735970-A | CONTAINING ADDUCT OF CARBON DIOXIDE, AMINE, AND WATER | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-05 | — | — | US | disclosed |