⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059979 | 0.81 | — | — | |
| SCHEMBL6545575 | 0.81 | — | — | |
| SCHEMBL285354 | 0.80 | — | — | |
| SCHEMBL6419715 | 0.80 | — | — | |
| SCHEMBL18541532 | 0.80 | — | — | |
| SCHEMBL2350696 | 0.80 | — | — | |
| SCHEMBL8652009 | 0.80 | — | — | |
| SCHEMBL727636 | 0.80 | — | — | |
| SCHEMBL1888683 | 0.78 | THRB (0.62) | — | |
| SCHEMBL25949401 | 0.78 | THRB (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693773-A | CAPABLE OF HYBRIDIZING TO AND INHIBITING EXPRESSION OF NUCLEIC ACIDS HAVING MIXED PURINE/PYRIMIDINE SEQUENCES BY TRIPLEX FORMATION; COMPRISES THREE REGIONS-DUPLEX FORMING REGION, TRIPLEX FORMING REGION AND LINKER REGION | HYBRIDON INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
| WO-1996040710-A1 | TRIPLEX-FORMING ANTISENSE OLIGONUCLEOTIDES HAVING ABASIC LINKERS TARGETING NUCLEIC ACIDS COMPRISING MIXED SEQUENCES OF PURINES AND PYRIMIDINES | HYBRIDON, INC. (US) | 1996-12-19 | — | — | WO | disclosed |