Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.70 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 5/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287283 | 0.91 | ITGB3 (0.65) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL5751261 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL3847073 | 0.81 | CYP1A2 (0.52) | ITGB3ITGA2BCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17440475 | 0.81 | ITGB3 (0.67) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL12324733 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL381083 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL29119874 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL1532653 | 0.79 | ITGB3 (0.64) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL5865021 | 0.79 | CYP1A2 (0.57) | ITGB3ITGA2BCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL27793739 | 0.79 | CYP1A2 (0.57) | ITGB3ITGA2BCYP1A2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | claimed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |