SCHEMBL381083

SCHEMBL381083

O=C(O)CCCC1CCNCC1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 11/20 0.66
ITGA2B P08514 11/20 0.66
FAAH O00519 1/20 0.49
SLC6A1 P30531 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRB2 P47870 2/20 0.48
SLC6A12 P48065 2/20 0.48
SLC6A11 P48066 2/20 0.48
SLC6A13 Q9NSD5 2/20 0.48
GABRA1 P14867 1/20 0.48
GABRR1 P24046 1/20 0.48
GABRA4 P48169 1/20 0.48
TPSAB1 Q15661 1/20 0.47
TPSD1 Q9BZJ3 1/20 0.47
TPSG1 Q9NRR2 1/20 0.47
F2R P25116 4/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
KDM5A P29375 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1532653 0.98 ITGB3 (0.64) ITGB3ITGA2BFAAHSLC6A1GABRA5
SCHEMBL5751261 0.94 ITGB3 (0.69) ITGB3ITGA2BFAAHSLC6A1GABRA5
SCHEMBL5501220 0.93 ITGB3 (0.59) ITGB3ITGA2BFAAHSLC6A1GABRA5
SCHEMBL17440475 0.92 ITGB3 (0.67) ITGB3ITGA2BFAAHSLC6A1GABRA5
Hydrochloric Acid SCHEMBL29119874 0.90 ITGB3 (0.65) ITGB3ITGA2BFAAHSLC6A1GABRA5
SCHEMBL5494841 0.88 SLC6A1 (0.60) ITGB3ITGA2BFAAHSLC6A1GABRA5
SCHEMBL954535 0.87 ITGB3 (0.56) ITGB3ITGA2BSLC6A1GABRA5GABRB2
SCHEMBL23909396 0.86 ITGB3 (0.60) ITGB3ITGA2BSLC6A1GABRA5GABRB2
Hydrochloric Acid SCHEMBL3159636 0.85 ITGB3 (0.54) ITGB3ITGA2BSLC6A1GABRA5GABRB2
SCHEMBL29193847 0.84 KDM5A (0.53) ITGB3ITGA2BSLC6A1GABRA5GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2023-08-01 US claimed
EP-3939972-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2022-01-19 EP claimed
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2021-11-04 US claimed
EP-3545978-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2021-09-08 EP claimed
US-10898598-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2021-01-26 US claimed
EP-3545978-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2019-10-02 EP claimed
EP-3300746-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2019-05-15 EP claimed
US-20190134237-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2019-05-09 US claimed
CN-105025933-B Triazine Radiopharmaceuticals and Radioimaging Agents 分子制药洞察公司 2019-03-26 CN claimed
US-10201624-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2019-02-12 US claimed
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-22 US claimed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US claimed
EP-1828240-B1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NAT RECH SCIENT (FR) 2009-07-29 EP claimed
US-7410949-B2 Genetically engineered truncated analogs of significantly lower-molecular-weight and having equal or better potency, pharmacokinetic properties and pharmacological properties as existing Y2R agonists; also pegylated analogs; treating obesity; dietetics; metabolic disorders HOFFMANN-LA ROCHE INC. (US) 2008-08-12 US claimed
JP-2008527017-A 2008-07-24 JP claimed
CN-101107266-A Peptides having neuropeptide-2 receptor (Y2R) agonist activity HOFFMANN LA ROCHE (CH) 2008-01-16 CN claimed
EP-1844070-A1 PEPTIDES WITH NEUROPEPTIDE-2 RECEPTOR (Y2R) AGONIST ACTIVITY F.HOFFMANN-LA ROCHE AG (CH) 2007-10-17 EP claimed
WO-2006077035-A9 PEPTIDES WITH NEUROPEPTIDE-2 RECEPTOR (Y2R) AGONIST ACTIVITY HOFFMANN LA ROCHE (CH) 2006-10-26 WO claimed
WO-2006077035-A1 PEPTIDES WITH NEUROPEPTIDE-2 RECEPTOR (Y2R) AGONIST ACTIVITY F.HOFFMANN-LA ROCHE AG (CH) 2006-07-27 WO claimed
US-20060160742-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof DANHO WALEED 2006-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 ITGB3 2256/4885ITGA2B 1367/4885FAAH 3627/4885
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CD40, CD40LG, TNFSF10 ITGB3 1229/4885ITGA2B 1360/4885FAAH 4564/4885
US-10898598-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 ITGB3 2256/4885ITGA2B 1367/4885FAAH 3627/4885
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 ITGB3 2256/4885ITGA2B 1367/4885FAAH 3627/4885
US-20060160742-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof NPY2R, NPY1R, NPY4R ITGB3 3703/4885ITGA2B 3345/4885FAAH 900/4885
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS TNFRSF1A, TNFRSF9, CD40 ITGB3 1120/4885ITGA2B 757/4885FAAH 3509/4885
US-10201624-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA5, PSMA2, PSMA1 ITGB3 3306/4885ITGA2B 2378/4885FAAH 2573/4885
US-20190134237-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 ITGB3 2256/4885ITGA2B 1367/4885FAAH 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.