Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283083 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7282562 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7277350 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7285264 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7284201 | 0.88 | ITGB3 (0.71) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7283166 | 0.88 | ITGB3 (0.71) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL8884076 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL7273994 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| SCHEMBL8863881 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BMMP2MMP3MMP1 | |
| Hydrochloric Acid SCHEMBL7281221 | 0.85 | ITGB3 (0.57) | ITGB3ITGA2BKDM4EIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |