Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275877 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL7283083 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BKDM4EALDH1A1IRAK4 | |
| SCHEMBL7282562 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BKDM4EALDH1A1IRAK4 | |
| SCHEMBL7276433 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BKDM4EALDH1A1IRAK4 | |
| SCHEMBL7277517 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BIRAK4DGAT1 | |
| Hydrochloric Acid SCHEMBL7284744 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BIRAK4DGAT1 | |
| SCHEMBL7285055 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EIRAK4DGAT1 | |
| SCHEMBL7337066 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EIRAK4DGAT1 | |
| SCHEMBL9261874 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2BKDM4EIRAK4DGAT1 | |
| Hydrochloric Acid SCHEMBL7278520 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |