Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283177 | 0.92 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7294041 | 0.91 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL8379088 | 0.91 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL8882836 | 0.90 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL7286033 | 0.89 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL7282972 | 0.89 | ITGB3 (0.86) | ITGB3ITGA2B | |
| Lamifiban SCHEMBL871446 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7274876 | 0.87 | ITGB3 (0.72) | ITGB3ITGA2B | |
| Lamifiban SCHEMBL4683 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7284509 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658928-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS,WOUND HEALING AGENTS, OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545658-A | FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION | HOFFMAN-LA ROCHE INC. (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0505868-B1 | N-Acyl-alpha-aminoacids derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-13 | — | — | EP | disclosed |
| US-5378712-A | Antithrombosis | Hoffmann-La Roche Inc (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0505868-A2 | N-Acyl-alpha-aminoacids derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-30 | — | — | EP | disclosed |