Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059399 | 0.86 | ALDH1A1 (0.42) | JAK2ALDH1A1 | |
| SCHEMBL13478888 | 0.85 | CHRM1 (0.42) | SLC6A4SLC6A2SLC6A3CHRM1GNAI3 | |
| SCHEMBL615680 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3CHRM1GNAI3 | |
| SCHEMBL19432668 | 0.84 | ALDH1A1 (0.49) | JAK2ALDH1A1 | |
| SCHEMBL22252442 | 0.82 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL3363066 | 0.81 | ALDH1A1 (0.54) | ALDH1A1 | |
| Acetic Acid SCHEMBL9471385 | 0.80 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3CHRM1ALDH1A1 | |
| SCHEMBL6969342 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3GNAI3GNAO1 | |
| SCHEMBL4157539 | 0.79 | CHRM1 (0.41) | SLC6A4SLC6A2SLC6A3CHRM1ALDH1A1 | |
| SCHEMBL13673385 | 0.79 | CHRM1 (0.44) | SLC6A4SLC6A2SLC6A3CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457686-B1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-08-03 | — | — | EP | disclosed |
| US-5214055-A | Analgesics, psychological disorders, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-05-25 | — | — | US | disclosed |
| US-5189045-A | Antiserotonine agent | ADIR ET COMPAGNIE (FR) | 1993-02-23 | — | — | US | disclosed |
| EP-0457686-A1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |