Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276895 | 0.98 | REN (0.68) | REN | |
| SCHEMBL7331904 | 0.90 | REN (0.66) | REN | |
| SCHEMBL9438009 | 0.86 | REN (0.53) | REN | |
| SCHEMBL7268886 | 0.85 | REN (0.69) | REN | |
| SCHEMBL7267778 | 0.85 | REN (0.66) | REN | |
| Acetic Acid SCHEMBL9326712 | 0.84 | REN (0.73) | REN | |
| SCHEMBL7276316 | 0.84 | REN (0.68) | REN | |
| SCHEMBL7331725 | 0.83 | REN (0.56) | REN | |
| Acetic Acid SCHEMBL9327753 | 0.83 | REN (0.71) | REN | |
| Acetic Acid SCHEMBL9325931 | 0.82 | REN (0.82) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360791-A | Renin-inhibiting aminodiol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0370454-B1 | Renin-inhibiting amino diol derivatives | HOECHST AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0370454-A2 | Renin-inhibiting amino diol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |