Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438108 | 0.91 | REN (0.50) | REN | |
| SCHEMBL9438027 | 0.91 | REN (0.53) | REN | |
| Hydrochloric Acid SCHEMBL9438095 | 0.90 | REN (0.52) | REN | |
| SCHEMBL7276895 | 0.88 | REN (0.68) | REN | |
| SCHEMBL9438069 | 0.86 | REN (0.50) | REN | |
| SCHEMBL7276816 | 0.86 | REN (0.67) | REN | |
| SCHEMBL9437959 | 0.85 | REN (0.57) | REN | |
| SCHEMBL9438195 | 0.82 | REN (0.49) | REN | |
| SCHEMBL9438008 | 0.81 | REN (0.49) | REN | |
| Hydrochloric Acid SCHEMBL9554504 | 0.81 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328916-A | Renin inhibitors, hypotensive agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0456039-A2 | Renin inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1991-11-13 | — | — | EP | disclosed |