Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202789 | 0.86 | LMNA (0.66) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 | |
| SCHEMBL17622943 | 0.86 | LMNA (0.66) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 | |
| Hydrochloric Acid SCHEMBL9225018 | 0.84 | LMNA (0.46) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 | |
| Hydrochloric Acid SCHEMBL9225014 | 0.84 | LMNA (0.46) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 | |
| SCHEMBL7285989 | 0.83 | LMNA (0.48) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 | |
| SCHEMBL7303511 | 0.77 | ALOX15 (0.50) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9220199 | 0.77 | ALOX15 (0.50) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9225572 | 0.75 | ALOX15 (0.49) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9225576 | 0.75 | ALOX15 (0.49) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7279895 | 0.74 | LMNA (0.37) | LMNAADORA3SMN1; SMN2L3MBTL1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580008-B1 | Phenylimidazolidine Derivatives, their preparation and use | HOECHST AG (DE) | 1998-07-08 | — | — | EP | disclosed |
| US-5424293-A | Anticoagulants of platelet aggregation; osteoclast antagonist for treating osteoporosis | CASSELLA AG (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0580008-A2 | Phenylimidazolidine Derivatives, their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | disclosed |