Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664477 | 0.78 | LMNA (0.34) | NPC1RAB9ALMNA | |
| SCHEMBL6228115 | 0.76 | FFAR3 (0.48) | MVDPHF8KDM2ANPC1RAB9A | |
| SCHEMBL2804753 | 0.76 | EPHX2 (0.46) | MVDPHF8KDM2ATDP1EPHX2 | |
| SCHEMBL6826759 | 0.75 | — | — | |
| SCHEMBL11737268 | 0.74 | MVD (0.41) | MVDPHF8KDM2ANPC1RAB9A | |
| SCHEMBL28427604 | 0.74 | PHF8 (0.41) | MVDPHF8KDM2ANPC1RAB9A | |
| SCHEMBL29434566 | 0.74 | SLC22A6 (0.50) | MVDPHF8KDM2AEPHX2LMNA | |
| SCHEMBL4590256 | 0.74 | MVD (0.41) | MVDPHF8KDM2ANPC1RAB9A | |
| SCHEMBL5664495 | 0.73 | — | — | |
| SCHEMBL6936379 | 0.72 | ALDH1A1 (0.58) | TDP1APPKMT2AEPHX2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024919-A1 | FUNCTIONALIZED SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-01-28 | — | — | US | claimed |
| US-20200256862-A1 | FUNCTIONALIZED SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-08-13 | — | — | US | claimed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | claimed |
| US-20210024919-A1 | FUNCTIONALIZED SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-01-28 | — | — | US | disclosed |
| US-20200256862-A1 | FUNCTIONALIZED SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-08-13 | — | — | US | disclosed |
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | disclosed |