Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277123 | 0.92 | ITGB3 (0.46) | ASAH1ITGB3ITGA2BALDH1A1TSHR | |
| SCHEMBL8881618 | 0.90 | KDM1A (0.41) | LMNAHPGDDGAT1OPRM1OPRD1 | |
| SCHEMBL7282695 | 0.90 | KDM1A (0.41) | LMNAHPGDDGAT1OPRM1OPRD1 | |
| SCHEMBL7275921 | 0.90 | KDM1A (0.41) | LMNAHPGDDGAT1OPRM1OPRD1 | |
| SCHEMBL7280929 | 0.88 | KDM1A (0.42) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7277853 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BLMNAHPGDDGAT1 | |
| SCHEMBL7275667 | 0.86 | DGAT1 (0.36) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7275656 | 0.86 | DGAT1 (0.36) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7284021 | 0.86 | DGAT1 (0.36) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7282719 | 0.84 | KDM1A (0.38) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |