Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879334 | 0.80 | MAPT (0.40) | DGAT1LMNAF2RL1 | |
| SCHEMBL2082227 | 0.79 | SMN1; SMN2 (0.35) | DGAT1 | |
| SCHEMBL18675311 | 0.76 | SMN1; SMN2 (0.34) | DGAT1F2RL1 | |
| SCHEMBL2082872 | 0.76 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL17275484 | 0.75 | DGAT1 (0.33) | DGAT1LMNAF2RL1 | |
| SCHEMBL4203399 | 0.73 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL2647731 | 0.73 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL9638271 | 0.72 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL9592717 | 0.72 | KCNH2 (0.37) | DGAT1 | |
| SCHEMBL32681724 | 0.71 | DGAT1 (0.36) | DGAT1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |