Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275375 | 0.82 | AAK1 (0.41) | PPIACYP1A2TDP1TSHR | |
| SCHEMBL7269535 | 0.82 | AAK1 (0.41) | PPIACYP1A2TDP1TSHR | |
| SCHEMBL8213601 | 0.73 | GAA (0.41) | GAASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL10871871 | 0.70 | NPC1 (0.39) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL8192515 | 0.69 | TSHR (0.43) | GAASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL24702068 | 0.69 | TSHR (0.45) | GAASMN1; SMN2L3MBTL1HPGDPOLB | |
| SCHEMBL1921112 | 0.68 | SMN1; SMN2 (0.59) | GAASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8203980 | 0.68 | TSHR (0.44) | GAASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL30890579 | 0.68 | HPGD (0.65) | GAASMN1; SMN2RAB9AHPGDPOLB | |
| SCHEMBL5593041 | 0.67 | RAB9A (0.39) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |