Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192515 | 0.85 | TSHR (0.43) | TSHRL3MBTL1TDP1HSD17B10HPGD | |
| SCHEMBL24702068 | 0.82 | TSHR (0.45) | TSHRL3MBTL1TDP1HSD17B10HPGD | |
| SCHEMBL3717247 | 0.76 | L3MBTL1 (0.43) | TSHRL3MBTL1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL20535766 | 0.74 | L3MBTL1 (0.40) | TSHRL3MBTL1TDP1HSD17B10HPGD | |
| SCHEMBL15212938 | 0.71 | ALDH1A1 (0.41) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL3405851 | 0.71 | APP (0.64) | TSHRL3MBTL1TDP1HSD17B10HPGD | |
| SCHEMBL28137293 | 0.71 | TSHR (0.51) | TSHRL3MBTL1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL28403527 | 0.71 | LMNA (0.47) | TSHRL3MBTL1HSD17B10HPGDALDH1A1 | |
| SCHEMBL11027264 | 0.70 | GAA (0.48) | TSHRL3MBTL1TDP1HSD17B10HPGD | |
| SCHEMBL30890579 | 0.70 | HPGD (0.65) | HSD17B10HPGDALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000169449-A | NEW PRODUCTION INTERMEDIATE FOR FLUORINE-CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVE | BANYU PHARMACEUT CO LTD | 2000-06-20 | — | — | JP | disclosed |