Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287003 | 0.95 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7284870 | 0.93 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7275380 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BITGA2ALDH1A1TSHR | |
| SCHEMBL7277328 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BITGA2ALDH1A1TSHR | |
| SCHEMBL7277017 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7274663 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7277666 | 0.83 | TMPRSS2 (0.41) | ITGB3ITGA2BHTR1A | |
| SCHEMBL7275263 | 0.83 | TMPRSS2 (0.41) | ITGB3ITGA2BHTR1A | |
| SCHEMBL9251785 | 0.83 | TMPRSS2 (0.41) | ITGB3ITGA2BHTR1A | |
| SCHEMBL7283983 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |